HIGH DOSE AMLODIPINE POISONING TREATED WITH HIGH INSULIN EUGLYCEMIC THERAPY
نویسندگان
چکیده
منابع مشابه
Lipid Rescue Therapy and High-Dose insulin Euglycemic Therapy are Effective for Severe Refractory Calcium Channel Blocker Overdose: Case Report and Review of Literature
Background: High-Dose Insulin Euglycemic Therapy (HIET) and Lipid Rescue Therapy (LRT) are new alternative treatments for acute poisoning with calcium channel blockers. In this report a severely poisoned patient with verapamil and furosemide who was successfully treated with these two treatments is presented. Case report: A 27-year-old woman was brought to “Mother Theresa” Clinical Center in Sk...
متن کاملA Case of Amlodipine Overdose: Role of High Dose Insulin Therapy
Calcium channel blockers (CCB) are a leading cause of mortality from drug overdose among cardiovascular medicine [1]. CCBs are commonly used for treating hypertension, angina, and arrhythmias. However in an overdose, this can lead to cardiogenic shock that is difficult to treat with vasopressors alone and is especially problematic for long-acting agents such as amlodipine. Insulin is widely use...
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Poisoning and overdose of beta-blockers may be associated with significant morbidity and mortality. Management is often complicated by failure of initial first-line interventions in severe ingestions. High-dose insulin, or hyperinsulinemia/euglycemia therapy has been well described in calcium channel blocker overdose as well as mixed ingestions of calcium channeland betablocker agents. The data...
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Overdoses of β-blockers and calcium channel blockers can produce significant morbidity and mortality, and conventional therapies often do not work as treatments for these poisonings. High-dose insulin/glucose therapy has been successful in reversing the cardiotoxic effects of these drugs in cases where the standard therapies have failed, and it appears to be relatively safe. Many successes have...
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ژورنال
عنوان ژورنال: Chest
سال: 2019
ISSN: 0012-3692
DOI: 10.1016/j.chest.2019.08.1936