High Concordance Between Two Companion Diagnostics Tests
نویسندگان
چکیده
منابع مشابه
Are companion diagnostics useful?
We define a companion diagnostics (CDx) test as any diagnostic tool that guides the selection of patient treatment. In the US, these tests include diagnostics cleared by the Food and Drug Administration (FDA), as well as laboratory-developed tests (LDTs) run in CLIA-accredited laboratories. The answer to the title’s question is obviously in the affirmative. We discuss the growing need to improv...
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At the European Multidisciplinary Cancer Congress (EMCC), held in Stockholm in September 2011, a recurring theme in many of the workshops was personalised medicine, including the latest developments in prognostic and predictive biomarkers. Such markers, it is hoped, will enable clinicians to use available resources to best effects-by offering treatments to only those patients most likely to ben...
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Companion diagnostic tests, developed for use in conjunction with therapeutic drugs and biologics, drive personalized medicine. These tests, which are regulated by the U.S. Food and Drug Administration as medical devices when they are marketed as kits,[1] are indispensable to personalized medicine because they provide “information that is essential for the safe and effective use of a correspond...
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MOTIVATION Due to advances in experimental technologies, such as microarray, mass spectrometry and nuclear magnetic resonance, it is feasible to obtain large-scale data sets, in which measurements for a large number of features can be simultaneously collected. However, the sample sizes of these data sets are usually small due to their relatively high costs, which leads to the issue of concordan...
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The goal of personalized medicine, to effectively customize diagnosis, treatment and prevention of disease to one’s genetic composition, is one that has been known and sought for many years. Increasingly, molecular companion diagnostics based on one’s inherited or somatic biomarkers are desired to ensure the effective, safe develop ment and application of a personalized drug. This has been ref...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2011
ISSN: 0002-9173,1943-7722
DOI: 10.1309/ajcpjpj8zwgdttwc