High-Capacity Drug Carriers from Common Polymer Amphiphiles
نویسندگان
چکیده
منابع مشابه
Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.
We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the linker group of drug amphiphiles on the drug release efficiency and their consequent in vitro efficacy.
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Colloidal drug carrier is one of the most important entities essentially required for successful transport of loaded drugs. They are drug vectors, which sequester, transport and retain the active drug en route, while they elute or deliver it within or in the vicinity of target. Targeting the drug to the desired site of action would not only improve the therapeutic efficacy but also enable a red...
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solid lipid carriers – NLC. Particulate lipid matrices in the form of lipid pellets are known from the textbooks since many years, products are on the market (e. g. Mucosolvan retard, Boehringer-Ingelheim). After these lipid pellets as the first generation, P. Speiser developed so-called “lipid nanopellets for oral administration” in the middle of the eighties [1]. This system was not further d...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2016
ISSN: 1525-7797,1526-4602
DOI: 10.1021/acs.biomac.6b00960