HIGH-CALORIE DIET DURING LACTATION PROGRAMS EARLY HYPERPHAGIA IN MALE AND FEMALE NEWBORN RATS

Obesity is a serious and concerning disease for public health. Breastfeeding crucial formetabolic programming plays an important role in controlling newborn metabolism. Theaim of this study was to analyze weight gain milk consumption male femalenewborn rats whose mothers were fed high-calorie diet during the breastfeeding period. Atdelivery, female Wistar divided into two groups, one hypercaloric diet(4,500 kcal/g sucrose solution at 10%; Ob group), while control dams fedcommertial (Cont group). Pups weighed every days, intake wasrecorded on 6 th , 11 16 days old. At 22 old, pups weaned, themother euthanized analysis. day olds, males consumed 42.7% moremilk than Cont, females 33.9% more Cont (P<0.001). On thday life, 33.9%more (P<0.05). day, 39.3% Cont(P<0.001), 29.8% (P<0.01). During thebreastfeeding period, there increase body mass by 21.7% (P<0.05) andin 10%. It observed that showed 18.65%compared (P<0.001), among group pups, no significantdifference between females. We concluded offspring breastfedby who lactation are likely developearly hyperphagia, greater risk developing obesity.