High anthracycline cumulative dose without cardiac toxicity: a possible protective role of morphine
نویسندگان
چکیده
منابع مشابه
The role of nitric oxide in anthracycline toxicity and prospects for pharmacologic prevention of cardiac damage.
Anthracycline antibiotics are potent antitumor agents whose activity is severely limited by a cumulative dose-dependent chronic cardiotoxicity that results from the summation of multiple biochemical pathways of cellular damage, which ultimately yields to disruption of myocardiocyte integrity and loss of cardiac function. Nitric oxide (NO) is a key molecule involved in the pathophysiology of hea...
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چکیده ارتباط در کلاس به عوامل زیادی از جمله معلمان، دانش آموزان، برنامه های درسی و از همه مهم تر، مواد آموزشی وابسته است. در تدریس ارتباطی زبان که تاکید زیادی بر توانش ارتباطی دارد، کتاب درسی به عنوان عامل موثر بر پویایی کلاس محسوب میگردد که درس ها را از طریق فراهم آوردن متن ارتباط کلاسی و هم چنین نوع تمرین زبانی که دانش آموزان در طول فعالیت های کلاسی به آن مشغول اند، کنترل می کند. این حقیقت ک...
15 صفحه اولMorphine priming rescues high-dose morphine-induced biological perturbations.
In in vitro studies, macrophage morphine priming (MP; preincubation with low-dose morphine) attenuated the effects of high-dose morphine (HDM) on macrophage capabilities of killing and containment of phagocytosed bacteria. In in vivo studies, mice received either normal saline (control), HDM, or MP twice daily for 10 consecutive days. All HDM-treated mice showed a significant peritoneal bacteri...
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ژورنال
عنوان ژورنال: The Anatolian Journal of Cardiology
سال: 2018
ISSN: 2149-2263
DOI: 10.14744/anatoljcardiol.2018.65481