High affinity of lead for fetal haemoglobin.
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منابع مشابه
High affinity of lead for fetal haemoglobin.
In-vitro experiments using 203Pb were performed to identify lead-binding components in human haemoglobin. Sephadex A-50 ion-exchange chromatography of haemolysate showed that different types of haemoglobin had different affinities for lead. For the haemolysate from adults, lead was present in both Hb A (alpha 2 beta 2) and Hb A2 (alpha 2 delta 2), whereas, in the haemolysate from new-born infan...
متن کاملPersistent fetal haemoglobin and falsely high glycosylated haemoglobin levels.
Some of the routine methods of measuring glycosylated haemoglobin depend on its difference in charge from haemoglobin A and do not distinguish between glycosylated haemoglobin and fetal haemoglobin. Two insulin dependent diabetics showed persistent discrepancies between their capillary blood glucose values and their glycosylated haemoglobin values measured by agar gel electrophoresis: the blood...
متن کاملBlood lead and haemoglobin in lead absorption.
a low haemoglobin but none had symptoms or signs that were likely to be due to lead absorption. A further i8 men had haemoglobins of 89% (13 g./Ioo ml.) or less. None was thought to be low due to lead absorption. The absence of symptoms, signs, and low haemoglobins in association with relatively high blood leads is unlikely to be due to errors in blood lead or haemoglobin estimation. Alternativ...
متن کاملDeterminants of fetal haemoglobin in newborn infants.
Percentage fetal haemoglobins (% HbF) were measured in 7081 newborns at the University Hospital, Nottingham, between 1990 and 1992 to assess the effects of a range of factors, and to determine if there was an association between % HbF at birth and risk of SIDS (sudden infant death syndrome). Data from the obstetric clinical records were analysed by multiple linear regression to establish the ma...
متن کاملThe therapeutic reactivation of fetal haemoglobin.
Unusually high levels of fetal haemoglobin production can ameliorate sickle cell disease and beta thalassaemia. Although efforts directed at the pharmacological stimulation of fetal haemoglobin as an approach to managing these conditions have met with limited success, there is wide variation in individual responses. Whether this reflects the particular mutations that underlie these conditions o...
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 1980
ISSN: 1351-0711
DOI: 10.1136/oem.37.3.292