HIERARCHICAL DEVELOPMENT OF PHYSICAL FRAILTY AND COGNITIVE IMPAIRMENT: CLUES INTO ETIOLOGICAL PATHWAYS
نویسندگان
چکیده
منابع مشابه
Characterisation of Physical Frailty and Associated Physical and Functional Impairments in Mild Cognitive Impairment
Objective To characterize the physical frailty phenotype and its associated physical and functional impairments in mild cognitive impairment (MCI). Method Participants with MCI (N = 119), normal low cognition (NLC, N = 138), and normal high cognition (NHC, N = 1,681) in the Singapore Longitudinal Ageing Studies (SLAS-2) were compared on the prevalence of physical frailty, low lean body mass, ...
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SIR—The global prevalence of dementia is rising with Alzheimer’s disease (AD) accounting for 50–60% of all cases and mild cognitive impairment (MCI) its precursor [1, 2]. Although the clinical hallmark of AD is progressive loss of memory and cognition, several studies have also shown changes in mobility and body composition suggesting frailty [3, 4]. Frailty represents age-related reduction in ...
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The relationship between frailty and cognitive impairment has been recognized for decades, but it was not until a few years ago that the interest in this relationship increased and is now being understood. Epidemiological evidence suggests that physical frailty may be linked to cognitive impairment since both conditions share pathophysiological mechanisms at the cellular and systemic levels. Ag...
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More than 50 years after Belding Scribner and colleagues made maintenance hemodialysis feasible for treatment of ESRD, it is easy to lose sight of the key role of rehabilitation in the care of ESRD patients that Dr. Scribner envisioned: “If the treatment of chronic uremia cannot fully rehabilitate the patient, the treatment is inadequate” (1). Early studies suggested that—contrary to Dr. Scribn...
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The aim was to evaluate associations between frailty status and cognitive decline and the incidence of cognitive impairment over 12-month period. Two hundred seven older adults were assessed. Frailty was defined as having at least three of the following criteria: weight loss, weakness, exhaustion, slowness, and low level of activity. Cognitive decline was assessed using the Mini Mental State Ex...
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ژورنال
عنوان ژورنال: Innovation in Aging
سال: 2018
ISSN: 2399-5300
DOI: 10.1093/geroni/igy023.083