منابع مشابه
Hibernoma--a rare brown fat tumour.
Hibernoma is a rare benign tumour of brown fat. It is also known as lipoma of brown adipose tissue, lipoma glandular and atypical lipoma. The hibernoma was first described by Merkelin 1906, who called it Pseudolipoma. The name hibernoma is derived from its histological similarity to the brown fat of hibernating animals. They have been found in the neck, back, popliteal space, thighs, axilla, ab...
متن کاملConcomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma.
Hibernomas are benign tumors with morphological features resembling brown fat. They consistently display cytogenetic rearrangements, typically translocations, involving chromosome band 11q13. Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor suppressor genes that are located 3 Mb apart and that underlie the hereditary syndromes pituitary...
متن کاملThe Lipid Composition of Hibernoma as Compared with That of Lipoma and of Mouse Brown Fat.
is the morphologic similarity between the tumor and this type of fat : like brown fat, hibernoma is composed, wholly or largely, of multivacuolated fat cells; and both are highly vascular (1). In this study the lipid composition of 2 hibernomas has been compared with that of ordinary lipomas and of mouse brown fat. 1\1ATERIAIS AND METHODS Two patients were operated on for a soft tissue tumor in...
متن کاملLaryngeal hibernoma: case series of a rare tumor.
BACKGROUND Hibernomas are rare, benign tumors of brown adipose tissue uncommonly found in the head and neck. METHODS A review of the English-language literature was conducted for this study. We present a series of 2 laryngeal hibernomas treated with transoral laser microsurgical resection at a tertiary referral center over a period of 18 years. RESULTS Only 2 cases of laryngeal hibernoma ha...
متن کاملHibernoma. A case report and discussion of a rare tumor.
A case report is presented of a large retroperitoneal hibernoma along with the clinical, radiographic, and pathologic findings. Despite the unusual size and location of this hibernoma, the case illustrates the salient features of these rare tumors of brown fat origin. Pitfalls in preoperative diagnosis are discussed. To date, there has been no convincing evidence of malignant potential of this ...
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ژورنال
عنوان ژورنال: Cancer
سال: 1952
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(195203)5:2<364::aid-cncr2820050226>3.0.co;2-8