منابع مشابه
Assessing Glucose Uptake through the Yeast Hexose Transporter 1 (Hxt1)
The transport of glucose across the plasma membrane is mediated by members of the glucose transporter family. In this study, we investigated glucose uptake through the yeast hexose transporter 1 (Hxt1) by measuring incorporation of 2-NBDG, a non-metabolizable, fluorescent glucose analog, into the yeast Saccharomyces cerevisiae. We find that 2-NBDG is not incorporated into the hxt null strain la...
متن کاملArsenic trioxide uptake by hexose permeases in Saccharomyces cerevisiae.
Arsenic trioxide is a toxic metalloid and carcinogen that is also used as an anticancer drug, and for this reason it is important to identify the routes of arsenite uptake by cells. In this study the ability of hexose transporters to facilitate arsenic trioxide uptake in Saccharomyces cerevisiae was examined. In the absence of glucose, strains with disruption of the arsenite efflux gene ACR3 ac...
متن کاملHexose uptake in Trypanosoma cruzi: structure-activity relationship between substrate and transporter.
The gene encoding a hexose transporter, TcrHt1, from Trypanosoma cruzi has been functionally expressed in mammalian Chinese hamster ovary cells. Kinetic parameters of the heterologously expressed protein are very similar to those of the transporter identified in T. cruzi epimastigotes, confirming that TcrHT1 is the major transporter functioning in these parasites. A detailed analysis of substra...
متن کاملModulation of Hexose Uptake and Insulin Action by Cell Membrane Fluidity
Temperature-induced alterations in membrane fluidity in rat adipocyte plasma membranes were evaluated by electron spin resonance spectroscopy and compared to temperature-induced alterations in hexose uptake and insulin binding. Thermal transition curves of the 5-doxylstearate spin probe in purified plasma membranes exhibit phase transitions at 25-26”C, 30-31”C, and 33-34°C. Glucose, 2-deoxy-D-g...
متن کاملShort-term effects of obestatin on hexose uptake and triacylglycerol breakdown in human subcutaneous adipocytes
AIM To study complete dose-dependent effects of obestatin on lipolytic and glucose transport activities in human adipocyte preparations highly responsive to insulin. METHODS Adipocytes were prepared by liberase digestion from subcutaneous abdominal adipose tissue obtained from overweight subjects undergoing plastic surgery. The index of lipolytic activity was the glycerol released in the incu...
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ژورنال
عنوان ژورنال: Reactome - a curated knowledgebase of biological pathways
سال: 2007
ISSN: 1934-1792
DOI: 10.3180/react_9441.1