Hexane fraction of Pluchea indica root extract inhibits proliferation and induces autophagy in human glioblastoma cells
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چکیده
منابع مشابه
Downregulation of Kinesin Spindle Protein Inhibits Proliferation, Induces Apoptosis and Increases Chemosensitivity in Hepatocellular Carcinoma Cells
Background: Kinesin spindle protein (KSP) plays a critical role in mitosis. Inhibition of KSP function leads to cell cycle arrest at mitosis and ultimately to cell death. The aim of this study was to suppress KSP expression by specific small-interfering RNA (siRNA) in Hep3B cells and evaluate its anti-tumor activity. Methods: Three siRNA targeting KSP (KSP-siRNA #1-3) and one mismatched-siRNA (...
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ژورنال
عنوان ژورنال: Biomedical Reports
سال: 2017
ISSN: 2049-9434,2049-9442
DOI: 10.3892/br.2017.979