Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues
نویسندگان
چکیده
منابع مشابه
Roles of Embryonic and Adult Lymphoid Tissue Inducer Cells in Primary and Secondary Lymphoid Tissues
The nomenclature "embryonic lymphoid tissue inducer (LTi) cell" reflects the fundamental role of the cell in secondary lymphoid tissue organization. In addition, it is equally important in primary lymphoid tissue development as it regulates central tolerance to self-antigens in the thymus. An adult LTi cell constitutively expresses two sets of tumor necrosis factor (TNF) family members, whereas...
متن کاملLymphoid tissue inducer cells
A model for other countries? Politicians and concerned citizens in other countries will observe Germany’s movements closely, as it is the first example of a high technology country turning its back on nuclear energy after using it for more than half a century. Around the world, many old and new users of nuclear reactors are sticking to their plans and policies, only adding a safety inspection h...
متن کاملHeterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
Lymphoid tissue inducer (LTi) cells have been characterized in mouse as a key cell when secondary lymphoid tissues are organized during development and memory T cells are formed after birth. In addition to their involvement in adaptive immune responses, recent studies show that they contribute to innate immune responses by producing large amount of interleukin (IL)-22 against microbial attack. ...
متن کاملLymphoid tissue inducer cells in intestinal immunity.
During fetal development, lymphoid tissue inducer cells (LTis) seed the developing lymph node and Peyer's patch anlagen and initiate the formation of both types of lymphoid organs. In the adult, a similar population of cells, termed lymphoid tissue inducer-like cells (LTi-like cells), supports the formation of organized gut-associated lymphoid tissue (GALT) in the intestine, including both isol...
متن کاملTransplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization
In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used to analyze the cellular and molecular requirements for the development and organization of splenic microenvironments. Whole embryonic day 15 (ED15) spleens, grafted under the kidney capsule of adult mice, were colonized by host-derived lymphocytes and DC and developed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Immunology
سال: 2008
ISSN: 0019-2805,1365-2567
DOI: 10.1111/j.1365-2567.2007.02750.x