Heterogeneity in ventilation during positive end-expiratory pressure

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Heterogeneity in ventilation during positive end-expiratory pressure

geneity in ventilation be good’ [1] and the related article by Zhao and colleagues [2]. We agree with the comments that instead of incremental positive end-expiratory pressure (PEEP) levels, a decremented PEEP titration might be an attractive option for determining optimal PEEP [1,3]. However, we feel that physiological inhomogeneity in ventilation and perfusion related to the gravitational eff...

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effect of positive end-expiratory pressure on central venous pressure in patients under mechanical ventilation

introduction: finding the probable governing pattern of peep and cvp changes is an area of interest for in-charge physicians and researchers. therefore, the present study was designed with the aim of evaluating the relationship between the mentioned pressures. methods: in this quasi-experimental study, patients under mechanical ventilation were evaluated with the aim of assessing the effect of ...

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Positive end-expiratory pressure.

PURPOSE OF REVIEW In the last 2 years, several reports have dealt with recruitment/positive end-expiratory pressure (PEEP) selection. Most of them confirm previous results and few add new information. RECENT FINDINGS It has been definitely confirmed that opening pressures are different throughout the acute respiratory distress syndrome lung parenchyma, ranging from 5-10 up to 30-40 cmH2O. The...

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Positive end-expiratory pressure and surfactant decrease lung injury during initiation of ventilation in fetal sheep.

The initiation of ventilation in preterm, surfactant-deficient sheep without positive end-expiratory pressure (PEEP) causes airway injury and lung inflammation. We hypothesized that PEEP and surfactant treatment would decrease the lung injury from initiation of ventilation with high tidal volumes. Fetal sheep at 128-day gestational age were randomized to ventilation with: 1) no PEEP, no surfact...

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Paradoxical responses to positive end-expiratory pressure in patients with airway obstruction during controlled ventilation.

OBJECTIVE To reevaluate the clinical impact of external positive end-expiratory pressure (external-PEEP) application in patients with severe airway obstruction during controlled mechanical ventilation. The controversial occurrence of a paradoxic lung deflation promoted by PEEP was scrutinized. DESIGN External-PEEP was applied stepwise (2 cm H(2)O, 5-min steps) from zero-PEEP to 150% of intrin...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2010

ISSN: 1364-8535

DOI: 10.1186/cc9212