Hereditary multiple cutaneous leiomyomatosis
نویسندگان
چکیده
منابع مشابه
Multiple Cutaneous and Uterine Leiomyomatosis
Multiple cutaneous and uterine leiomyomatosis (MCUL: OMIM 150800), which is also known as Reed syndrome, is an autosomal dominant disorder in which benign skin tumors arising from the arrector pili muscle and uterine fibroids typically develop in the third and fourth decades [1, 2]. Reed et al first reported on two families in which members of successive generations demonstrated cutaneous leiom...
متن کاملHereditary leiomyomatosis and renal cell cancer: Cutaneous lesions & atypical fibroids
Objective To report a diagnosis of hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome following initial presentation with multiple cutaneous lesions. Design Case report. Design classification N/A. Setting Academic tertiary care center. Patients 27-year-old nulligravid woman who presented with multiple red-brown lesions on her skin found to have cutaneous and uterine leiomy...
متن کاملHereditary leiomyomatosis and renal cell carcinoma
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal-dominant hereditary syndrome, which is caused by germline mutations in the FH gene that encodes the tricarboxylic acid cycle enzyme fumarate hydratase (FH). HLRCC patients are predisposed to develop cutaneous leiomyomas, multiple, symptomatic uterine fibroids in young women resulting in early hysterectomies, and early on...
متن کامل[Hereditary leiomyomatosis and renal cell cancer].
Presentamos el caso de una paciente de 52 años, cuya hermana ha sido recientemente diagnosticada de una mutación heterocigota del gen FH asociado a leiomiomatosis hereditaria y cáncer de células renales. La hermana fue estudiada por la presencia de leiomiomas cutáneos múltiples y una historia de miomas uterinos, por los que precisó histerectomía. Nuestra paciente es una mujer sana cuyo único an...
متن کاملCutaneous leiomyomatosis in a mother and daughter*
A 34-year-old woman with no known medical history was evaluated for multiple painful brown nodules and papules on the anterior aspect of the trunk. She mentioned a history of similar cutaneous findings on her mother. Biopsies of three lesions revealed piloleiomyomata. Renal and adrenal ultrasound revealed an isolated simple cortical cyst, and pelvic and endovaginal ultrasound revealed two uteri...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/44598