Hereditary Angio-Oedema: Treatment with Cl Esterase Inhibitor Concentrate
نویسندگان
چکیده
منابع مشابه
Hereditary angio-oedema
Hereditary angio-oedema is caused by a heterozygous deficiency of C1 inhibitor. This inhibitor regulates several inflammatory pathways, and patients with hereditary angio-oedema have intermittent cutaneous or mucosal swellings because of a failure to control local production of bradykinin. Swellings typically evolve in several hours and persist for a few days. In addition to orofacial angio-oed...
متن کاملCurrent management of hereditary angio-oedema (C'1 esterase inhibitor deficiency).
Hereditary angio-oedema is characterised by recurrent swellings in any part of the body and also by recurrent attacks of severe abdominal pain. The disease is inherited in an autosomal dominant manner but up to 25% of cases can occur as a spontaneous mutation. Attacks of swelling can be precipitated by trauma, certain drugs, and emotional stress. Treatment usually involves a combination of prop...
متن کاملHereditary angio-oedema with mesangiocapillary glomerulonephritis.
A patient with hereditary angio-oedema (HAO) developed mesangiocapillary glomerulonephritis (MCGN) under observation. HAO is characterized by an inherited defect of complement-deficiency of C1 esterase. MCGN is often associated with another complement abnormality which leads to depression of serum C3 and there is some evidence that the complement abnormality precedes the nephritis. The coincide...
متن کاملHepatocellular carcinoma after danazol treatment for hereditary angio-oedema.
Hereditary angio-oedema is characterised by recurrent episodes of laryngeal, intra-abdominal, facial or peripheral oedema. Danazol can be used as prophylaxis for recurrent attacks. Hepatotoxicity is a recognised adverse effect of danazol. We report an exceptional case of a danazol-induced hepatocellular carcinoma in a 75-year-old patient with hereditary angio-oedema.
متن کاملRecurrent intestinal obstruction with acquired angio-oedema, due to C1-esterase inhibitor deficiency.
A 52-year male with past history of ulcerative colitis 20 years back (now in remission), developed recurrent small intestinal obstruction at intervals of a few months. CT scan did not detect the cause initially. A repeat CT scan (USA) showed interbowel fluid with transient ascites (serum albumin normal). Angio-oedema was suspected and low C4 with C1-esterase inhibitor (C1-INH) deficiency confir...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1984
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107688407701213