Hepatorenal protective effect of ocimum sanctum in chickens toxicated by gentamicin
نویسندگان
چکیده
Background: ocimum sanctum (Tulsi) “Queen of herbs†is considered as sacred and medicinal plant in a lot countries around the world especially India. Therefore this study was carried out to investigate heptorenal protective effect aqueous extract against gentamicin induced hepatorenal toxicity chickens.Materials Methods: A total 100, one-day old unsexed broiler chicks commercial breed (Cobb breed) were used study, chickens subjected different treatments blood tissue samples collected at 5th week age post administration, biochemical histopathological examinations utilized on liver kidney.Results: recorded significant (P<0.05)increase serum level aspartate aminotransferase (AST), alanine (ALT), uric acid creatinine levels when compared with control group, administration ameliorate their toxic effect, group treated only similar control, while induce (P<0.05)decrease albumin, protein globulin restore effect. The control. Gentamicin alterations kidney tissues by comparison showing improvement lesion gentamicin.Conclusions: hepatotoxicity nephrotoxicity ameliorated dose 2ml/liter drinking water for 12 days. Â
منابع مشابه
Immunomodulatory effect of Ocimum sanctum in broilers treated with high doses of gentamicin
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ژورنال
عنوان ژورنال: International journal of pharmacology and toxicology
سال: 2021
ISSN: ['2310-2985']
DOI: https://doi.org/10.14419/ijpt.v9i1.31421