Hepatitis C virus genotype 6: Virology, epidemiology, genetic variation and clinical implication

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Hepatitis C virus genotype 6: virology, epidemiology, genetic variation and clinical implication.

Hepatitis C virus (HCV) is a serious public health problem affecting 170 million carriers worldwide. It is a leading cause of chronic hepatitis, cirrhosis, and liver cancer and is the primary cause for liver transplantation worldwide. HCV genotype 6 (HCV-6) is restricted to South China, South-East Asia, and it is also occasionally found in migrant patients from endemic countries. HCV-6 has cons...

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Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV infection can progress to severe liver disease including cirrhosis and hepatocellular carcinoma. In the last decade, our basic understanding of HCV virology and life cycle has advanced greatly with the development ...

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Molecular biology and clinical implication of hepatitis C virus.

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2014

ISSN: 1007-9327

DOI: 10.3748/wjg.v20.i11.2927