Hepatitis C genotype 6: A concise review and response-guided therapy proposal
نویسندگان
چکیده
منابع مشابه
Response-guided therapy for patients with hepatitis C virus genotype 6 infection: a pilot study.
The optimal duration of treatment with pegylated interferon (PEG-IFN) plus ribavirin (RBV) in patients with hepatitis C virus (HCV) genotype 6 is unknown. This study was aimed at determining treatment response on the basis of rapid virological response (RVR) of HCV genotype 6 in comparison with genotypes 1 and 3. Sixty-six treatment naïve patients were treated with PEG-IFN-α2a (180 μg/week) plu...
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OBJECTIVE To determine compliance and improvement in sustained viral response (SVR) by following response guided therapy (RGT) plan of interferon and ribavirin, for genotype 3 in chronic hepatitis C. METHODS Patients with chronic hepatitis C genotype 3, who were eligible for interferon-ribavirin therapy and consented for RGT, were included. Those with no rapid viral response (RVR), having coa...
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Research produces highly efficient antiviral drugs. At the same time, viruses develop sophisticated strategies to evade their actions. Resistance to antiviral therapy has become a major issue in the management of patients with chronic viral infections. The best known example is human immunodeficiency virus (HIV), but cytomegalovirus, herpes simplex virus, and hepatitis B and C viruses exhibit s...
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Retrospective analyses of the boceprevir and telaprevir phase 3 trial data demonstrate the clinical relevance of detected but not quantifiable hepatitis C virus (HCV) genotype 1 RNA during treatment. These analyses illustrate the importance of using precise and standard terminology in reporting low-level HCV RNA results for consistent data collection across clinical trials, and to ensure optima...
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Chronic hepatitis C virus (HCV)b infection is a major public health problem, affecting over 2.7 million individuals in the U.S. and over 170 million worldwide [1, 2]. In the United States, HCV infection is the most common cause of chronic liver disease, accounts for 8,000 to 10,000 deaths annually, and is the leading indication for liver transplantation [3]. Since the initial discovery of HCV v...
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ژورنال
عنوان ژورنال: World Journal of Hepatology
سال: 2013
ISSN: 1948-5182
DOI: 10.4254/wjh.v5.i9.496