Hepatic stereology of schistosomiasis mansoni infected-mice fed a high-fat diet
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منابع مشابه
Hepatic stereology of Schistosomiasis mansoni infected-mice fed a high-fat diet.
High-fat diets induce weight gain and fatty liver in wild-type mice. Schistosomiasis mansoni infection also promotes hepatic injury. This study was designed to quantify hepatic alterations in schistosomiasis mansoni-infected mice fed a high fat-rich chow compared to mice fed a standard rodent chow, using stereology. Female SW mice fed each either high-fat diet (29% lipids) or standard chow (12%...
متن کاملEffect of praziquantel administration on hepatic stereology of mice infected with Schistosoma mansoni and fed a low-protein diet.
A study was undertaken to investigate the effect of administering praziquantel (PZQ), focusing on the liver stereological findings of malnourished mice infected with Schistosoma mansoni. Thirty female Swiss Webster mice (age: 21 days; weight: 8-14 g) were fed either a low-protein diet (8%) or standard chow (22% protein) for 15 days. Five mice in each group were infected with 50 cercariae each o...
متن کاملHigh fat diet has a prominent effect upon the course of chronic schistosomiasis mansoni in mice.
This study investigated whether a long-term high-fat diet has an effect on the outcome of chronic murine schistosomiasis mansoni compared to a standard diet. Swiss Webster female mice (3 weeks old) were fed each diet for up to six months and were then infected with 50 Schistosoma mansoni cercariae. Their nutritional status was assessed by monitoring total serum cholesterol and body mass. Infect...
متن کاملProgressive adaptation of hepatic ketogenesis in mice fed a high-fat diet.
Hepatic ketogenesis provides a vital systemic fuel during fasting because ketone bodies are oxidized by most peripheral tissues and, unlike glucose, can be synthesized from fatty acids via mitochondrial beta-oxidation. Since dysfunctional mitochondrial fat oxidation may be a cofactor in insulin-resistant tissue, the objective of this study was to determine whether diet-induced insulin resistanc...
متن کاملSuppression of hepatic dysfunction in tenascin-X-deficient mice fed a high-fat diet
Extracellular matrix glycoprotein tenascin‑X (TNX) is the largest member of the tenascin family. In the present study, the contribution of TNX to liver dysfunction was investigated by administration of high‑fat and high‑cholesterol diet with high levels of phosphorus and calcium (HFCD) to wild‑type (WT) and TNX‑knockout (KO) mice. After 16 weeks of HFCD administration, the ratio of liver weight...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2006
ISSN: 0074-0276
DOI: 10.1590/s0074-02762006000900039