Henoch-SchÖlein Purpura Nephritis in Children: A Severe IgA Mediated Glomerulonephritis

Henoch-Schönlein purpura nephritis.

Henoch-Schönlein purpura (HSP) is a systemic vasculitic disorder first reported by Heberden in 1806. The association of purpura and joint pain was described by Schönlein in 1837, who termed it “peliosis rheumatica.” Henoch added a description of four children with skin lesions associated with colicky abdominal pain, gastrointestinal hemorrhage, and joint pain in 1874, and in 1899 pointed out th...

Azathioprine treatment in two children with Henoch–Schönlein purpura nephritis

Henoch-Schönlein purpura nephritis in children: incidence, pathogenesis and management.

BACKGROUND Henoch-Schönlein purpura (HSP) is one of the most common vasculitides in children. It is manifested by skin purpura, arthritis, abdominal pain, renal involvement, etc. Typically, HSP is considered to be self-limiting, although renal involvement (HSP purpura nephritis, HSPN) is the principal cause of morbidity from this disease. For this reason, it is important to clarify the mechanis...

درمان کودک مبتلا به نفریت هنوخ شوئن لاینه‌ای با مایکوفنولیت مافتیل cellcept))

 Received: 18 Aug, 2008 Accepted: 14 Feb, 2009  Abstract  Renal involvement is one of the most serious sequela of Henoch-Schönlein purpura. The presence of proteinuria (nephritic range) and hematuria is also associated with progression to renal insufficiency. In fifty percent of patients who display a combination of nephritis-nephrotic symptoms, end-stage disease develops. Pharmacologic treatme...

Henoch-Schönlein Purpura Nephritis in Childhood

Henoch-Schönlein purpura is one of the most common causes of systemic vasculitis. Henoch–Schönlein purpura typically affects children between the age of 3 and 10 years. The aetiology is unknown. Diagnosis includes palpable purpura (essential) in the presence of diffuse abdominal pain, acute arthritis/arthralgia, renal involvement characterized by haematuria and/or proteinuria (Ozen et al., 2006...