Henna: A cause of life threatening hemolysis in G6PD-deficient patient

Can acetaminophen cause hemolysis in G6PD deficiency?

Henna: a potential cause of oxidative hemolysis and neonatal hyperbilirubinemia.

OBJECTIVE To evaluate the in vitro oxidation potential of lawsone (2-hydroxy-1,4 naphthoquinone). Lawsone is a chemical present in henna, the crushed leaves of which are used worldwide as a cosmetic agent to stain the hair, skin, and nails. METHODOLOGY Venous blood from glucose-6-phosphate dehydrogenase (G6PD)-normal and G6PD A- subjects were incubated with various amounts of lawsone for 2 ho...

Excess release of ferriheme in G6PD-deficient erythrocytes: possible cause of hemolysis and resistance to malaria.

Hemoglobin in glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes is abnormally vulnerable to oxidative denaturation, which may release ferriheme, a known cytolytic agent. We found 13.3 nmol of ferriheme in G6PD-deficient erythrocyte membranes (per gram of total erythrocyte hemoglobin) using a spectrophotometric assay, as compared to 9.8 in normal membranes (P less than .05). After ...

Methemoglobinemia and intravascular hemolysis in a patient with G6PD deficiency.

Naphthalene Induced Acute Hemolysis in A G6PD Deficient Bangladeshi Boy - A Case Report

Naphthalene (C10 H8) is a bicyclic aromatic hydrocarbon having 128 molecular weight [1]. Usually it is used as a deodorant in lavatories, moth repellent and as insecticides, mite powders and vermifuges [2]. In Bangladesh, a developing country, naphthalene is very popular and widely used moth repellent. People use it freely in household as it is very cheap and easily available. Naphthalene is ma...