Hemophagocytic syndrome in patients with unexplained cytopenia: report of 15 cases

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Hemophagocytic syndrome in patients with unexplained cytopenia: report of 15 cases.

OBJECTIVE To investigate the frequency of hemophagocytic syndrome in a series of patients with otherwise unexplained cytopenia. MATERIAL AND METHOD In this cross-sectional, single-centre study, bone marrow specimens (n=288) were obtained from the patients with unexplained cytopenia. The diagnosis of hemophagocytic syndrome was made according to universally accepted criteria. Characteristics o...

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Autoimmune Lymphoproliferative Syndrome Misdiagnosed as Hemophagocytic Lymphohistiocytosis A Case Report

Autoimmune lymphoproliferative Syndrome (ALPS) is a rare inherited disorder of apoptosis. It usually presents with chronic lymphadenopathy, splenomegaly, and symptomatic cytopenia in a child. Herein, we report a 14-year-old boy with symptoms misdiagnosed as hemophagocytic lymphohistiocytosis who was treated before ALPS was diagnosed for the patient. This case should alert pediatricians to consi...

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Netherton syndrome is a rare autosomal recessive condition with variable expression. It comprises an ichthyosiform dermatitis and erythroderma of variable intensity associated with hair abnormalities and features of atopy. The pathognomic (required for diagnosis) feature is trichorrhexis invaginata identified by microscopic examination of hair shaft. Ichthyosis linearis circumflexa is ano...

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ژورنال

عنوان ژورنال: Turkish Journal of Pathology

سال: 2013

ISSN: 1018-5615,1309-5730

DOI: 10.5146/tjpath.2013.01142