Hemolysis Interference in the Ortho-Clinical Diagnostics Vitros ECi cTnI Assay
نویسندگان
چکیده
منابع مشابه
Analytical and clinical performance of the Ortho-Clinical Diagnostics VITROS amino-terminal pro-B type natriuretic peptide assay.
BACKGROUND Measurement of amino-terminal pro-B-type natriuretic peptide (NT-proBNP) is useful for evaluating patients with heart failure (HF). METHODS We evaluated the performance of a new automated NT-proBNP assay. RESULTS The VITROS NT-proBNP assay had mean within-run and total imprecision of 1.0% and 3.4% at NT-proBNP concentrations from 67-27,500 ng/l. Acceptable linearity, functional/a...
متن کاملSemiautomated method for determination of cystine concentration in polymorphonuclear leukocytes.
higher) than the analytical sensitivity, allowing for acceptable clinical specificity. Furthermore, there was excellent clinical concordance between the Vitros ECi and Dade RxL cTnI assays. The cTnI values obtained with the ECi were approximately one-half of the those obtained with the RxL cTnI, probably because of the lack of antigen and antibody standardization between assays (4 ). Thus, the ...
متن کاملFunctional sensitivity and recovery of thyroid-stimulating hormone.
To the Editor: Comparisons of the Vitros ECi thyroid-stimulating hormone (TSH) method with the AxSym (1 ), Immulite (1, 2), Elecsys (2 ), and ADVIA Centaur (2 ) have shown an unexplained progressive negative bias ,0.2 mIU/L, a phenomenon that we have also observed (Fig. 1A). To investigate the bias, we diluted the TSH International Reference Preparation 80/558 (predominately pituitary TSH) and ...
متن کاملS100B protein in clinical diagnostics: assay specificity.
1. van Schaik RHN, van der Heiden IP, van den Anker JN, Lindemans J. CYP3A5 variant allele frequencies in Dutch Caucasians. Clin Chem 2002;48:1668– 71. 2. van Schaik RHN, de Wildt SN, van Iperen NM, Uitterlinden AG, van den Anker JN, Lindemans J. CYP3A4-V polymorphism detection by PCR-restriction fragment length polymorphism analysis and its allelic frequency among 199 Dutch Caucasians. Clin Ch...
متن کاملFalse-Positive Total T3 Using the Ortho Vitros Immunoassay in Pediatric Populations
TO THE EDITOR: Total triiodothyronine (T3) (TT3) measurements can provide clinical utility elucidating T3-dominant Graves' disease and other thyrotoxicosis conditions. Thyroid hormone assays, including TT3, are susceptible to protein-based interferences, usually caused by endogenous antibodies. Interferences should be considered when the thyroid hormone concentrations are inconsistent with clin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2003
ISSN: 0009-9147,1530-8561
DOI: 10.1373/49.7.1226