Hemodynamics of protamine administration
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چکیده
منابع مشابه
Evidence for Inhibition With Chronic Protamine Administration
In contrast to young growing animals, pressure-overload hypertrophy in adults is frequently associated with diminished myocardial capillary density and maximal coronary flow per gram. To determine the role of angiogenesis in maintaining perfusion capacity in the hypertrophying heart, the angiogenesis inhibitor protamine sulfate was administered to young lambs during the development of left vent...
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EDITORIALS 211 inotropic agents (such as the catecholamines, calcium ions, and digitalis), and paired electrical stimulation. Entropy also increases during congestive heart failure, which may be thought of as an expression of a defect in the utilization of energy, a partial chemicomechanical uncoupling. The entropy of the myocardial cell tends to be reduced by negative inotropic agents, such as...
متن کاملUse of nitric oxide for treatment of pulmonary hypertensive crisis in a child after protamine administration.
Introduction: Protamine is widely used to reverse heparin. However, protamine administration may cause systemic hypotension, pulmonary hypertension, anaphylactic shock, and cardiovascular collapse. (1) In one recent pediatric study, the only reaction seen was systemic hypotension. This was associated with small heparin dose, large protamine dose, and female gender with an incidence of 1.76%-2.8...
متن کاملSuccessful Treatment of Anaphylactic Shock after Protamine Administration-Report of a Case
A 43-year-old man, with a past history of hypertension without regular medical control, presented to our hospital with intermittent chest tightness and shortness of breathing about one day. At emergent department, the blood pressure was 180/110 mmHg, and pulse rate was 78 beats per minute. Troponin I was 3.19 ng/ml. EKG showed V1-V4 ST elevation. Coronary angiography showed near total occlusion...
متن کاملEffect of site of venous protamine administration, previously alleged risk factors, and preoperative use of aspirin on acute protamine-induced pulmonary vasoconstriction.
OBJECTIVE To determine whether the incidence of protamine-induced pulmonary vasoconstriction (PIPV) is influenced by central venous versus peripheral venous infusion of protamine and whether aspirin ingestion within a week of surgery would decrease the incidence of PIPV. DESIGN Single-institution, prospective, observational, randomized trial. SETTING University teaching hospital. PARTICIP...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1987
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)36160-4