Hematopoietic potential cells in skeletal muscle
نویسندگان
چکیده
منابع مشابه
Hematopoietic potential of stem cells isolated from murine skeletal muscle.
We have discovered that cells derived from the skeletal muscle of adult mice contain a remarkable capacity for hematopoietic differentiation. Cells prepared from muscle by enzymatic digestion and 5-day in vitro culture were harvested, and 18 x 10(3) cells were introduced into each of six lethally irradiated recipients together with 200 x 10(3) distinguishable whole bone marrow cells. After 6 or...
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Skeletal muscle damaged by injury or by degenerative diseases such as muscular dystrophy is able to regenerate new muscle fibers. Regeneration mainly depends upon satellite cells, myogenic progenitors localized between the basal lamina and the muscle fiber membrane. However, other cell types outside the basal lamina, such as pericytes, also have myogenic potency. Here, we discuss the main prope...
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Satellite cells are myogenic stem cells responsible for the post-natal growth, repair and maintenance of skeletal muscle. This review focuses on the basic biology of the satellite cell with emphasis on its role in muscle repair and parallels between embryonic myogenesis and muscle regeneration. Recent advances have altered the long-standing view of the satellite cell as a committed myogenic ste...
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Usually mathematicians use Hodgkin-Huxley model or FitzHug-Nagumo model to simulate action potentials of skeletal muscle fibers. These models are electrically excitable, but skeletal muscle fibers are stimulated chemically. To investigate skeletal muscle fibers we use a model with six ordinary differential equations. This dynamical system is sensitive to initial value of some variables so it is...
متن کاملIsolation and optimization of mice skeletal muscle satellite cells using preplating method and culture media substitution
Introduction: Satellite cells are known as the main regenerative cell type in skeletal muscles. Our study established a modified digestion and preplating method for the isolation of slow or weak adherent cells for the enrichment of satellite cells. Low-survival rate of these primary stem cells prompted us to address whether cell culture medium substitution might change cell viability status. M...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2007
ISSN: 1001-0602,1748-7838
DOI: 10.1038/cr.2007.88