Helicobacter pylori overcomes natural immunity in repeated infections
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori overcomes natural immunity in repeated infections
Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially thera...
متن کاملManagement of Helicobacter pylori infections
BACKGROUND Infection with Helicobacter pylori is associated with severe digestive diseases including chronic gastritis, peptic ulcer disease, and gastric cancer. Successful eradication of this common gastric pathogen in individual patients is known to prevent the occurrence of peptic ulcer disease and gastric cancer. DISCUSSION With half of the world's population being infected with H, pylori...
متن کاملMolecular mimicry in Helicobacter pylori infections
Gram-negative bacteria Helicobacter pylori (H. pylori) colonize gastric mucosa in humans and increase the risk of serious diseases such as gastric and duodenal ulcers, stomach cancers and mucosa associated lymphoid tissue lymphoma. The role of H. pylori infection in the pathogenesis of several extragastric diseases has been suggested including immune thrombocytopenic purpura, iron deficiency an...
متن کاملThe Relationship between Helicobacter Pylori and Extra-Gastrointestinal Infections
Helicobacter pylori (H. pylori) has been identified as the major agent in human gastric cancer by the International Agency for Research on Cancer (IARC). Infection caused by H. pylori plays a leading role in many disorders including duodenal and gastric ulcer, chronic gastritis, lymphoid tissue lymphoma, and gastric adenocarcinoma. In addition, growing evidence suggests that H. pylori interfere...
متن کاملNatural and experimental Helicobacter infections.
Current information about Helicobacter infections in humans and various domestic, wild, and research animal species that have been used or have the potential to be used as animal models of human disease is presented. The Helicobacter genus now includes at least 26 formally named species, with additional novel species in the process of being characterized. The natural history, host range with zo...
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ژورنال
عنوان ژورنال: Clinical Case Reports
سال: 2016
ISSN: 2050-0904,2050-0904
DOI: 10.1002/ccr3.687