منابع مشابه
Catalase, a novel antigen for Helicobacter pylori vaccination.
The efficacy of an orogastric vaccine comprised of purified Helicobacter pylori catalase plus the mucosal adjuvant cholera toxin (CT) was examined with both the Helicobacter felis and H. pylori mouse models with BALB/c mice. Native H. pylori catalase (200 microg) plus CT was initially used as a vaccine antigen in the H. felis mouse model and protected 80% (8 of 10) of the challenged animals, wh...
متن کاملA bioinformatics assay on Catalase epitopes of Helicobacter pylori
Niloufar Rashidi , Hajieh Gh. Safaei Department of medical laboratory sciences, Faculty of paraMedicine, Ahvaz jundishapour University of Medical Sciences, Ahvaz, Iran Department of Microbiology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran * Presenter & Corresponding author Abstract: Introduction: T cell responses are stimulated by the presence of short peptides b...
متن کاملVacuolating Cytotoxin of Helicobacter pylori
Vacuolating cytotoxin (VacA) is one of the most important virulence factors of H. pylori (Hp), which isthe only toxic protein that is secreted from Hp cell into the culture supernatant. The effects of VacA oneukaryotic systems is the subject of many previous and on going research studies. Intracellular targetsfor this toxin include: late endosomal and lysosomal compartments, m...
متن کاملProduction of IFN-γ and IL-4 Against Intact Catalase and Constructed Catalase Epitopes of Helicobacter pylori From T-Cells
BACKGROUND Helicobacter pylori infection is highly prevalent in the developing countries. It causes gastritis, peptic ulcer disease, and gastrocarcinoma. Treatment with drugs and antibiotics is problematic due to the following reasons: cost, resistance to antibiotics, prolonged treatment and using multiple drugs. Catalase is highly conserved among the Helicobacter species and is important to th...
متن کاملHelicobacter pylori
BRUCE E. DUNN,* HARTLEY COHEN, AND MARTIN J. BLASER Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226-0509; Pathology and Laboratory Medicine Service, Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295-1000; Gastroenterology and Liver Diseases Division, Department of Medicine, University of Southern California School of Medicine, Los ...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1991
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-137-1-57