Heat-shock resistance in experimental cryptorchid testis of mice
نویسندگان
چکیده
منابع مشابه
17beta-estradiol stimulates proliferation of spermatogonia in experimental cryptorchid mice.
AIM To investigate whether estrogen stimulates the proliferation of spermatogonia or induces spermatogenesis in cryptorchid mice. METHODS Mice were surgically rendered cryptorchid, then treated with different doses of 17beta-estradiol (E2) s.c. once a day. Mice were killed at sexual maturity (45 days of age), and histological analysis and immunofluorescence were performed. Serum follicle stim...
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Cryptorchidism is a known predisposing factor for the development of testicular tumors in adults. Age of patient at the time of treatment of undescended testes has some bearing on the risk of neoplasia. Testicular neoplasia at the time of primary surgery for cryptorchidism has been reported rarely in prepubertal period. We report a case where embryonal carcinoma was detected in a cryptorchid te...
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A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range and lactate dehydrogenase was raised. Computed tomography of the abdomen and pelvis revealed righ...
متن کاملHeat Shock Proteins Enriched-Promastigotes of Leishmania major Inducing Th2 Immune Response in BALB/c Mice
Background: Heat shock proteins (HSP) are highly conserved molecules with many immunological functions. They are highly immunogenic with important role in cancer immunotherapy and in vaccine development against infectious diseases. As adjuvant, HSP can augment the immunogenicity of weak antigens and can stimulate antigen presenting cells. Although vaccines have been successful for many infec...
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The incidence of testicular cancer in cryptorchidism is 30 to 50 times higher than in general population. We present a case of hydronephrosis caused by a seminoma in an abdominal cryptorchid testis. A 22 years old male presented abdominal and right flank pain, and haematuria. Despite the fact that he could not feel right testis since he was 7 years old, he had never looked for treatment. A huge...
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ژورنال
عنوان ژورنال: Molecular Reproduction and Development
سال: 2000
ISSN: 1040-452X,1098-2795
DOI: 10.1002/1098-2795(200102)58:2<216::aid-mrd11>3.0.co;2-c