Head-to-nerve analysis of electromechanical impairments of diffuse axonal injury

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Diffuse axonal injury in head trauma.

Diffuse axonal injury (DAI) as defined by detailed microscopic examination was found in 34 of 80 consecutive cases of head trauma surviving for a sufficient length of time to be clinically assessed by the Royal Adelaide Hospital Neurosurgery Unit. The findings indicate that there is a spectrum of axonal injury and that one third of cases of DAI recovered sufficiently to talk between the initial...

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Diffuse Axonal Injury in Head Trauma

Background: Diffuse axonal injury (DAI) is one of the most common and important pathologic features of traumatic brain injury (TBI). The susceptibility of axons to mechanical injury appears to be due to both their viscoelastic properties and their high organization in white matter tracts. Although axons are supple under normal conditions, they become brittle when exposed to rapid deformations a...

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evaluation of the effect of glibenclamide in patients with diffuse axonal injury due to moderate to severe head trauma

objectives we aim to evaluate the role of glibenclamide on the short-term outcome of patients with dai due to moderate to severe tbi. patients and methods in this controlled randomized clinical trial, 40 patients with moderate to severe tbi were assigned to glibenclamide (n = 20) and control (n = 20) groups. six hours after admission the intervention group received 1.25 mg glibenclamide every 1...

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Cognitive sequelae of diffuse axonal injury.

BACKGROUND The results of recent studies on cognitive disability after traumatic brain injury-associated diffuse axonal injury (DAI) are inconsistent. In these studies, the diagnosis of DAI relied on cranial computed tomography. OBJECTIVE To further clarify the extent and severity of a possibly DAI-associated cognitive impairment by the use of magnetic resonance imaging (MRI) and detailed neu...

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Prevalence of MR evidence of diffuse axonal injury in patients with mild head injury and normal head CT findings.

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ژورنال

عنوان ژورنال: Biomechanics and Modeling in Mechanobiology

سال: 2018

ISSN: 1617-7959,1617-7940

DOI: 10.1007/s10237-018-1086-8