منابع مشابه
ApoA-II/apoA-I molar ratio in the HDL particle influences phospholipid transfer protein-mediated HDL interconversion.
Pig plasma phospholipid transfer protein (PLTP) facilitates interconversion of both human HDL3 and pig HDL into HDL subpopulations of large and small particles. We recently suggested that there are two essential parts in the conversion mechanism, i.e., the release of apoA-I and phospholipids and the fusion of apoA-I-depleted unstable particles. Based on their mass composition and electrophoreti...
متن کاملThe Triglyceride-to-HDL Cholesterol Ratio
OBJECTIVE We evaluated whether the triglyceride-to-HDL cholesterol (TG/HDL-C) ratio is associated with insulin resistance (IR) in a large multiethnic cohort of obese youths. RESEARCH DESIGN AND METHODS Obese youths (1,452) had an oral glucose tolerance test and a fasting lipid profile. Insulin sensitivity was estimated using the whole body insulin sensitivity index (WBISI) and homeostasis mod...
متن کاملHDL Particle Size and Functional Heterogeneity.
Classic clinical and epidemiological studies have long ago established the presence of an inverse relationship between high-density lipoprotein cholesterol (HDLC) levels and cardiovascular disease (CVD) risk, and thus, it was assumed that measures that increase HDLC levels would afford protection against atherosclerosis-based CVD. However, trials of drugs, such as cholesterol ester transfer pro...
متن کاملWaist-to-height ratio (WHtR) and triglyceride to HDL-C ratio (TG/HDL-c) as predictors of cardiometabolic risk.
INTRODUCTION The excessive concentration of fat in the abdominal region is related to a higher risk of developing cardiovascular disease (CVD). Studies have been performed to identify simple and effective indicators of abdominal obesity and associated cardiometabolic risk through the use of simple parameters such as anthropometric and biochemical measures. The Triglyceride / High-density Lipopr...
متن کاملRatio of triglycerides to HDL cholesterol is an indicator of LDL particle size in patients with type 2 diabetes and normal HDL cholesterol levels.
OBJECTIVE In patients with type 2 diabetes, a normal HDL cholesterol level does not rule out that LDL particles may be small. Although techniques for analyzing LDL subfractions are not likely to be used in clinical practice, a prediction of LDL size based on a regular lipid profile may be useful for assessment of cardiovascular risk. RESEARCH DESIGN AND METHODS Sixty patients with type 2 diab...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2015
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2014.11.018