‘Have you packed your toothbrush?’

Have You Tested Your Goldmann Tonometer Today?

Intraocular pressure (IOP) is the only known modifiable risk factor for glaucoma. Besides being a cornerstone in glaucoma management, accurate measurement of IOP forms an important component of routine ophthalmic evaluation. Despite the innovation of various newer tonometers, Goldmann applanation tonometer is still considered the Gold standard for IOP measurement. However, there are several rep...

Have you stress tested your assay?

OBJECTIVES When a clinical assay is stressed with extraordinarily high volume of specimens over a short period of time, extra caution may be needed to avoid systematic errors and biases. Here we report our experience with a HgbA1c assay used for high volume wellness screening purpose, to illustrate the importance of stress testing during assay validation. DESIGN AND METHODS Over 15,000 whole ...

Have you had your mammogram, doctor?

Have you really addressed your patient's concerns?

As family physicians, we often strive to provide patient-centered care and place great value on communicating effectively with patients. We get to know our patients, their families and their concerns over time, and very often patients appreciate the care they receive. Despite our efforts, however, between 30 percent and 80 percent of patients’ expectations are not met in routine primary care vi...

HYSYS: have you swapped your samples?

Motivation The application of a genomics assay to samples from a cohort is a frequently applied experimental design in cancer genomics studies. The collection and analysis of cancer sequencing data in the clinical setting is an elaborate process that may involve consenting patients, obtaining possibly-multiple DNA samples, sequencing and analysis. Many of these steps are manual. At any stage mi...