Harvey Cushing Treated the First Known Patient With Carney Complex

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Harvey Cushing Treated the First Known Patient With Carney Complex

Context Carney complex (CNC) is a syndrome characterized by hyperplasia of endocrine organs and may present with clinical features of Cushing syndrome and acromegaly due to functional adrenal and pituitary gland tumors. CNC has been linked to mutations in the regulatory subunit of protein kinase A type I-alpha (PRKAR1A) gene. Design Tissue samples were taken from the hypothalamus or thalamus ...

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ژورنال

عنوان ژورنال: Journal of the Endocrine Society

سال: 2017

ISSN: 2472-1972

DOI: 10.1210/js.2017-00283