HandAlign: Bayesian multiple sequence alignment, phylogeny and ancestral reconstruction
نویسندگان
چکیده
منابع مشابه
HandAlign: Bayesian multiple sequence alignment, phylogeny and ancestral reconstruction
UNLABELLED We describe handalign, a software package for Bayesian reconstruction of phylogenetic history. The underlying model of sequence evolution describes indels and substitutions. Alignments, trees and model parameters are all treated as jointly dependent random variables and sampled via Metropolis-Hastings Markov chain Monte Carlo (MCMC), enabling systematic statistical parameter inferenc...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2012
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bts058