Haemorrhagic diathesis in children associated with vitamin K deficiency

Haemorrhagic diathesis in children associated with vitamin K deficiency.

A haemorrhagic diathesis is described in infants; this is preceded and accompanied by constitutional symptoms such as fever, diarrhoea, vomiting, anorexia, and pallor. These children had a severe coagulation abnormality, due to deficiency of vitamin-K-dependent coagulation factors, and it was corrected by administration of vitamin K. No conclusion could be drawn as to the aetiology of this cond...

Haemorrhagic diathesis due to deficiency of factor VII.

Of recent years it has become apparent that Quick's one-stage prothrombin time, although a most useful routine laboratory test, does not specifically measure plasma prothrombin. Quick himself (1947) recognized that deficiency of his labile factor (Factor V) caused lengthening of the prothrombin time, and Owren (1947) reported the first case of congenital deficiency of Factor V causing a haemorr...

Vitamin D Deficiency and its Relation with Cancer in Children

Vitamin D deficiency is known as the most common nutritional deficiency. It is created during infancy due to different factors, including decreased dietary intake, decreased dermal synthesis, malabsorption, enzyme-inducing medications, and exclusive breastfeeding. Vitamin D deficiency is associated with poor bone health such as rickets and osteomalacia in children. Despite vitamin D plays an im...

Albinism with haemorrhagic diathesis: Hermansky-Pudlak syndrome.

Four cases of albinism with haemorrhagic diathesis (Hermansky-Pudlak syndrome) are presented. The cases displayed wide phenotypic variation. Electroretinography was performed on all four patients and was found to be normal. One patient developed a cutaneous malignant melanoma.

Idiopathic hypoprothrombinemia associated with hemorrhagic diathesis, and the effect of vitamin K.