Haemopoietic precursor cell toxicity of mitoxantrone
نویسندگان
چکیده
منابع مشابه
Haemopoietic precursor cells in experimental hypoplastic marrow failure.
Following ti period of treahnent with Itii-siilphau, mice sustaine<l a prolonged or pfrnianent residual injury to the marrow. Thi.s was characteriwd l)y a decrease in nuinht'r of pluripotential .stein cells (CFU) and granulocytic pn»Henitor cells (CFC). Eventually, many mice developed frank marrow failure, and when this had occurred the numbers of CFL' and CFC were found to he even more markedl...
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Recently, the size of the active stem cell pool has been predicted to scale allometrically with the adult mass of mammalian species with a 3/4 power exponent, similar to what has been found to occur for the resting metabolic rate across species. Here we investigate the allometric scaling of human haemopoietic stem cells (HSCs) during ontogenic growth and predict a linear scaling with body mass....
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Department of Virology, University College London School of Life and Medical Sciences, London, Department of Virology, King’s College Hospital, London, Department of Haematology, Freeman Road Hospital, Newcastle, West of Scotland specialist virology centre, Gartnavel General Hospital, Glasgow, Birmingham HPA Laboratory, Birmingham Heartlands Hospital, Birmingham, Department of Haematology, King...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Clinical Oncology
سال: 1986
ISSN: 0171-5216,1432-1335
DOI: 10.1007/bf02580209