Haematological consequences of placental insufficiency

Placental Insufficiency.

The histopathology of placental insufficiency.

Voltaire, regarded by some as a realist and by others as a cynic, remarked that 'if God did not exist it would be necessary to invent him'. One suspects that this comment is equally applicable to placental insufficiency, a concept that has similarly attracted not only faithful adherence but also bewildered agnosticism or defiant disbelief. Placental insufficiency has been largely defined in cli...

Outpatient management of placental insufficiency with heparin.

1t has been demonstrated that continuous administration of heparin during pregnancy results in an improvement of placental insufficiency [l, 2, 3, 4, S]. This is based on the assumption that the nutritional insufficiency is caused maintained by a disturbance in the microcirculation due to platelet aggregation and fibrin deposits. By inhibiting these coagulation processes the disturbances of met...

Fetal responses to placental insufficiency: an update.

Disturbance of normal fetal growth can result in a decrease in weight, or altered body proportion at birth. Fetuses that fail to reach their genetically predetermined growth potential due to intrauterine growth restriction (IUGR) following placental insufficiency are at increased risk for adverse short and long term outcomes that can extend all the way into adult life. Because of its diverse im...

Placental insufficiency and fetal growth restriction.

OBJECTIVES Fetal growth restriction is defined as a pathologic decrease in the rate of fetal growth. The most frequent etiology for late onset fetal growth restriction is uteroplacental dysfunction which is due to inadequate supply of nutrients and oxygen to support normal aerobic growth of the fetus. However, for symmetrical IUGR, fetal chromosomal anomalies, structural anomalies and fetal inf...