Habituation of exploratory behaviour in VPA rats: animal model of autism
نویسندگان
چکیده
منابع مشابه
Habituation of exploratory behaviour in VPA rats: animal model of autism
Autism is a neurodevelopmental disorder with multifactorial aetiology, represented as impairment in social behaviour, communication and the occurrence of repetitive activities, which can be observed in the early life. The core features are frequently accompanied by other manifestations, including limited environmental exploration. The aim of the presented study, realised on an animal model of a...
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Acetylcholine (Ach) is a neurotransmitter considered to play a critical role in processes underlying behavior, learning, and memory. Pyritinol (pyrithioxine, Encephabol, PRT) is a nootropic drug that increases cholinergic transmission in the central nervous system. Behavioral habituation following multiple exposures to an open field is an experimental paradigm frequently used to assess the cogn...
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Autism is a neurodevelopmental condition diagnosed by impaired social interaction, abnormal communication and, stereotyped behaviors. While post-mortem and imaging studies have provided good insights into the neurobiological symptomology of autism, animal models can be used to study the neuroanatomical, neurophysiological and molecular mediators in more detail and in a more controlled environme...
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ژورنال
عنوان ژورنال: Interdisciplinary Toxicology
سال: 2013
ISSN: 1337-9569,1337-6853
DOI: 10.2478/intox-2013-0033