H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis
نویسندگان
چکیده
منابع مشابه
The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population.
BACKGROUND Mutations in HFE, a gene defect that can disrupt iron metabolism, have been implicated in increasing the risk of developing amyotrophic lateral sclerosis (ALS). OBJECTIVE To further establish the association between ALS and HFE mutations by investigating whether HFE mutations are associated with an increased risk of developing ALS in a population in The Netherlands and by pooling o...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2014
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2014.09.016