GYRB – POLYMERASE CHAIN REACTION AND HISTOPATHOLOGIC CHARACTERISTIC FIGURE POTENTIAL FOR DETERMINING DIAGNOSIS OF TUBERCULOUS LYMPHADENITIS

Background: TB lymphadenitis is still a problem that needs serious treatment. In Indonesia, it was reported 53% of cases were extrapulmonary tuberculosis, with the most being Lymphadenitis TB, 11.6%. children, 43% tuberculosis are lymphadenitis. Diagnosis quite difficult; method determining diagnosis and appropriate comprehensive treatment required in managing Lymphadenitis. Materials Methods: this study, 15 fine needle aspiration biopsy aspirate samples subjected to molecular examination using gyrB–polymerase chain reaction histopathological observations smear hematoxylin-eosin staining. Observation preparations microscope magnification 200x. Results: The characteristics showed positive results 4 out samples, epithelioid cells arranged characteristic granuloma structure, necrotic debris visible, joined together form multinucleated giant as an inflammatory response Mycobacterium tuberculosiscomplex infection. 6 (40%) detected be based on detection specific target gene gyrB - polymerase reaction. Conclusion: Characteristic features associated can used determinant tuberculous