Gut Reaction: Pyrosequencing Provides the Poop on Distal Gut Bacteria

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Gut Reaction: Pyrosequencing Provides the Poop on Distal Gut Bacteria

The human distal gut hosts a bustling community comprising thousands of different kinds of bacteria. Fortunately, most of these intestinal residents don’t cause disease but instead play key roles in nutrition, metabolism, pathogen resistance, and immune response regulation. Unfortunately, these beneficial bacteria are just as susceptible to the antibiotics we take to treat pathogenic bacteria. ...

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Gut reaction

The image above shows immunofluorescence staining of a cross-section of small intestine from a mouse with a 'mosaic' pattern of expression of cell-surface MHC (major histocompatibility complex) class I molecules. The mosaic effect can be seen on the intestinal villi, which contain stretches of epithelial cells that express MHC class I (bright green) interrupted by equally long stretches of cell...

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ژورنال

عنوان ژورنال: PLoS Biology

سال: 2008

ISSN: 1545-7885

DOI: 10.1371/journal.pbio.0060295