Gut microbiota and pediatric obesity/non-alcoholic fatty liver disease
نویسندگان
چکیده
منابع مشابه
Non-alcoholic fatty liver disease, diet and gut microbiota
Non-alcoholic fatty liver disease (NAFLD) is a severe liver disease that is increasing in prevalence with the worldwide epidemic of obesity and its related insulin-resistance state. Evidence for the role of the gut microbiota in energy storage and the subsequent development of obesity and some of its related diseases is now well established. More recently, a new role of gut microbiota has emerg...
متن کاملGut microbiota and non-alcoholic fatty liver disease: new insights.
Non-alcoholic fatty liver disease (NAFLD) is a severe liver disease that is increasing in prevalence with the worldwide epidemic of obesity and its related insulin-resistance state. A 'two-hit' mechanism has been proposed; however, the complete physiopathogenesis remains incompletely understood. Evidence for the role of the gut microbiota in energy storage and the subsequent development of obes...
متن کاملNon-alcoholic fatty liver and the gut microbiota
BACKGROUND Non-alcoholic fatty liver (NAFLD) is a common, multi-factorial, and poorly understood liver disease whose incidence is globally rising. NAFLD is generally asymptomatic and associated with other manifestations of the metabolic syndrome. Yet, up to 25% of NAFLD patients develop a progressive inflammatory liver disease termed non-alcoholic steatohepatitis (NASH) that may progress toward...
متن کاملGut microbiota and nonalcoholic fatty liver disease
Recent evidence has linked obesity and the metabolic syndrome with gut dysbiota. The precise mechanisms underlying that association are not entirely understood; however, microbiota can enhance the extraction of energy from diet and regulate whole-body metabolism towards increased fatty acids uptake from adipose tissue and shift lipids metabolism from oxidation to de novo production. Obesity and...
متن کاملPediatric Non-Alcoholic Fatty Liver Disease
Edgard Delvin CHU Sainte-Justine Research Center, 3175 Côte Ste-Catherine, Montreal, Quebec, Canada, H3T 1C5 e-mail: delvineasympatico.ca. Tel: (450) 681-1715 Summary: The rapidly increasing prevalence of childhood obesity and its associated co-morbidities such as hypertriglyceridemia, hyper-insulinemia, hypertension, early atherosclerosis, metabolic syndrome, and non-alcoholic fatty liver dise...
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ژورنال
عنوان ژورنال: Journal of the Formosan Medical Association
سال: 2019
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2018.11.006