منابع مشابه
A gut feeling about plasmablasts.
6 conserved aspartate residues (designated " D " in amino acid notation) in the molecule (see figure) are permissive to change, but the other 2 (D109 and D156) are critical for function with resulting marked impairment or total loss of function when mutated. Why aspartate? This amino acid is more highly conserved than others because of several attributes that include a short side chain, a high ...
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The gut microbiota of patients recently diagnosed with rheumatoid arthritis is enriched in microbes belonging to the Prevotella genus.
متن کاملA gut feeling about multiple sclerosis.
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS) that constitutes the leading cause of neurologic disability in young adults (1). Th1 and Th17 effector T cells (Teffs) are thought to play a central role in the pathogenesis of MS (2, 3). Thus, the study of the mechanisms that control Teffs and the regulatory T cells (Tregs) that suppress them is l...
متن کاملA Gut Feeling About Developmental Programming Mechanisms
It is now widely recognized that perinatal exposure to maternal dysmetabolic conditions may influence cardiovascular diseases in offspring. Maternal hypercholesterolemia, in particular, increases the susceptibility to atherosclerosis in humans and experimental models. The translational relevance of developmental programming is obvious. If safe interventions in hypercholesterolemic mothers befor...
متن کاملClinicians’ gut feeling about serious infections in children: observational study
OBJECTIVE To investigate the basis and added value of clinicians' "gut feeling" that infections in children are more serious than suggested by clinical assessment. DESIGN Observational study. SETTING Primary care setting, Flanders, Belgium. PARTICIPANTS Consecutive series of 3890 children and young people aged 0-16 years presenting in primary care. MAIN OUTCOME MEASURES Presenting featu...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2010
ISSN: 1945-3477
DOI: 10.1038/scibx.2010.1342