Guppy Y Chromosome Integrity Maintained by Incomplete Recombination Suppression
نویسندگان
چکیده
منابع مشابه
Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation
Sex chromosomes evolve once recombination is halted between a homologous pair of chromosomes. The dominant model of sex chromosome evolution posits that recombination is suppressed between emerging X and Y chromosomes in order to resolve sexual conflict. Here we test this model using whole genome and transcriptome resequencing data in the guppy, a model for sexual selection with many Y-linked c...
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Homologous recombination (HR) is used in vertebrate somatic cells for essential, RAD51-dependent, repair of DNA double-strand-breaks (DSBs), but inappropriate HR can cause genome instability. A transcriptional transactivation-independent role for p53 in suppressing HR has been established, but is not detected in all HR assays. To address the basis of such exceptions, and the possibility that su...
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2020
ISSN: 1759-6653
DOI: 10.1093/gbe/evaa099