Guided bone regeneration with osteoconductive grafts and PDGF: A tissue engineering option for segmental bone defect reconstruction
نویسندگان
چکیده
منابع مشابه
A Review on Commonly Used Scaffolds in Tissue Engineering for Bone Tissue Regeneration
Introduction: Bone is one of the tissues that have a true potential for regeneration. However, sometimes the bone defects are so outsized that there is no chance of bone self-repair and restoration or the damage is such that it is not possible to repair with medical or surgical interventions. In these situations, bone grafts are the treatment of choice, but due to several obstacles, including l...
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Guided bone regeneration (GBR) is a reconstructive procedure of alveolar ridge using membranes. This procedure is indicated when there is no sufficient bone for implantation, or in the case of optimal implant installation for esthetic or functional needs. GBR can be performed before implant placement, when there is not enough bone for initial stability of implants and less predictable outcomes ...
متن کاملReconstruction of a Critical Sized Segmental Bone Defect in the Ovine Tibia by Tissue Engineering Methods
Currently, well-established clinical therapeutic approaches for segmental bone defect reconstruction are restricted to the transplantation of autografts and allografts, and the implantation of metal devices or ceramic-based implants to assist bone regeneration. Bone grafts possess osteoconductive, osteoinductive, and osteogenic properties, but face significant disadvantages. These include limit...
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Biological mechanism of bone repair mainly involves both osteoconductivity and osteoinductivity. Scaffolds with osteoinductivity can give biological signals to stimulate the proliferation and differentiation of bone marrow mesenchymal stem cells and osteoblast-like cells to promote bone regeneration. Although most scaffolds for bone tissue engineering demonstrate osteoconductivity, they lack os...
متن کاملBone Tissue Engineering and Regeneration
1 Department of Surgery, University of Michigan Health Systems, Taubman Center, 1500 East Medical Center Drive, XPC 5340, Ann Arbor, MI 48109-0219, USA 2Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, 615 Charles E. Young Drive South, Room 410, Los Angeles, CA 90095, USA 3 Center for Cardiovascular Science and MRC Center for Regenerat...
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ژورنال
عنوان ژورنال: Journal of Applied Biomaterials & Functional Materials
سال: 2021
ISSN: 2280-8000,2280-8000
DOI: 10.1177/2280800020987405