GUANINEDESOXYPENTOSIDE FROM THYMUS NUCLEIC ACID

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منابع مشابه

On Thymus Nucleic Acid

A consideration of the earlier investigations of the nucleic acids would lead us to the conclusion that these substances yield among their hydrolytic products four purin derivatives, namely, xanthin, hypoxanthin, guanin, and adenin. Of these four bases hypoxanthin was the first discovered in this connection and was for a long time looked upon as the most constant in its occurrence, and, therefo...

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Nucleic acid helix-coil transitions mediated by helix-unwinding proteins from calf thymus.

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Nucleic Acid Helix-Coil Transitions Mediated by Helix-unwinding Proteins from Calf Thymus”

We have studied nucleic acid double helix destabilization mediated by purified calf helix-unwinding proteins, measuring ultraviolet hyperchromicity to detect helix melting. Both,calf unwinding protein 1 (UPl) and a high salt eluting protein fraction are found to depress strongly the helix melting temperature (T,) of the synthetic alternating copolymers poly[d(AT) ] and poly[r(AU)], indicating t...

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Nucleic Acid Helix-Coil Transitions Mediated by Helix-unwinding Proteins from Calf Thymus”

We have studied nucleic acid double helix destabilization mediated by purified calf helix-unwinding proteins, measuring ultraviolet hyperchromicity to detect helix melting. Both,calf unwinding protein 1 (UPl) and a high salt eluting protein fraction are found to depress strongly the helix melting temperature (T,) of the synthetic alternating copolymers poly[d(AT) ] and poly[r(AU)], indicating t...

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Purification and physical characterization of nucleic acid helix-unwinding proteins from calf thymus.

We have devised a general protein fractionation procedure which selects for eukaryotic DNA-binding proteins, some of which resemble DNA-unwinding proteins from prokaryotes. Proteins were selected which (a) pass through a native DNA-cellulose column, (b) bind to a denatured DNA-cellulose column, and (c) remain bound to the latter column during a rinse with a dilute solution of the sodium salt of...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1929

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)63722-6