GTH 2021 State of the Art—Cardiac Surgery: The Perioperative Management of Heparin-Induced Thrombocytopenia in Cardiac Surgery
نویسندگان
چکیده
Abstract Heparin-induced thrombocytopenia (HIT) is a severe, immune-mediated, adverse drug reaction that paradoxically induces prothrombotic state. Particularly in the setting of cardiac surgery, where full anticoagulation required during cardiopulmonary bypass, management HIT can be highly challenging, and requires multidisciplinary approach. In this short review, different perioperative strategies to run bypass will summarized.
منابع مشابه
Heparin-induced thrombocytopenia and cardiac surgery.
Unfractionated heparin given during cardiopulmonary bypass is remarkably immunogenic, as 25% to 50% of postcardiac surgery patients develop heparin-dependent antibodies during the next 5 to 10 days. Sometimes, these antibodies strongly activate platelets and coagulation, thereby causing the prothrombotic disorder, heparin-induced thrombocytopenia. The risk of heparin-induced thrombocytopenia is...
متن کاملHeparin-induced thrombocytopenia in cardiac surgery and critically ill patients.
Thrombocytopenia as well as anti-platelet factor 4/heparin (PF4/H) antibodies are common in cardiac surgery patients and those treated in the intensive care unit. In contrast, heparin-induced thrombocytopenia (HIT) is uncommon in these populations (~1 % and ~0.5 %, respectively). A stepwise approach where testing for anti-PF4/H antibodies is performed only in patients with typical clinical symp...
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Heparin induced thrombocytopenia presents as an underdiagnosed condition with life threatening thrombotic complications. The incidence in cardiac surgery patients is dependent on several factors and appeared to be greater in procedures that involve the use of intraaortic balloon pump. Clinical diagnosis is particularly challenging in cardiac surgery patients due to the natural occurrence of pos...
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ژورنال
عنوان ژورنال: Hamostaseologie
سال: 2021
ISSN: ['0720-9355', '2567-5761']
DOI: https://doi.org/10.1055/a-1336-6116