Growing old(er) with postinfectious bronchiolitis obliterans

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Growing old(er) with postinfectious bronchiolitis obliterans.

Most healthy children shrug off viral respiratory tract infections with little difficulty or assistance and a full recovery is the norm. A small minority, in contrast, are left with serious consequences. Important among these is postinfectious bronchiolitis obliterans (pBO) characterised by persistent—and sometimes severe—airway obstruction with functional and radiological evidence of small air...

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In the present report, we describe an unusual presentation of post-infectious bronchiolitis obliterans accompanied by pulmonary hemosiderosis in a nine-year-old boy with persistent respiratory symptoms subsequent to an episode of acute bronchiolitis occurring at the age of seven months. After the episode, the persistent respiratory symptoms worsened significantly, and, by the age of seven, the ...

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Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation

Postinfectious bronchiolitis obliterans (PIBO) is an irreversible obstructive lung disease characterized by subepithelial inflammation and fibrotic narrowing of the bronchioles after lower respiratory tract infection during childhood, especially early childhood. Although diagnosis of PIBO should be confirmed by histopathology, it is generally based on history and clinical findings. Irreversible...

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Bronchiolitis obliterans organizing pneumonia.

Bronchiolitis obliterans organizing pneumonia (BOOP) is increasingly recognized as an important cause of diffuse infiltrative lung disease. It is a diagnostic consideration in patients with a febrile flu-like illness of a few weeks' duration and a roentgenogram showing bilateral patchy infiltrates that are not responsive to a typical course of antibiotics. It is defined as granulated tissue plu...

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Bronchiolitis fibrosa obliterans.

Bronchiolitis fibrosa obliterans, described first by Lange in 1901, is an obliterative process of the bronchioles in which there is extensive damage to the bronchial wall involving all the constituent elements (the epithelium, elastic tissue, and muscle fibres), and the lumen is partially or totally occluded by bronchial exudate organized by fibroblasts and capillaries. The disease is extremely...

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ژورنال

عنوان ژورنال: Thorax

سال: 2014

ISSN: 0040-6376,1468-3296

DOI: 10.1136/thoraxjnl-2014-206168