Grouper TRADD Mediates Innate Antiviral Immune Responses and Apoptosis Induced by Singapore Grouper Iridovirus (SGIV) Infection
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منابع مشابه
JNK1 Derived from Orange-Spotted Grouper, Epinephelus coioides, Involving in the Evasion and Infection of Singapore Grouper Iridovirus (SGIV)
c-Jun N-terminal kinase (JNK) regulates cellular responses to various extracellular stimuli, environmental stresses, pathogen infections, and apoptotic agents. Here, a JNK1, Ec-JNK1, was identified from orange-spotted grouper, Epinephelus coioides. Ec-JNK1 has been found involving in the immune response to pathogen challenges in vivo, and the infection of Singapore grouper iridovirus (SGIV) and...
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Singapore grouper iridovirus (SGIV), a major pathogen of concern for grouper aquaculture, has a dsDNA genome with 162 predicted open reading frames, of which a total of 62 SGIV proteins have been identified. One of these, ORF158L, bears no sequence homology to any other known protein. Knockdown of orf158L using morpholino antisense oligonucleotides resulted in a significant decrease of virus yi...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2019
ISSN: 2235-2988
DOI: 10.3389/fcimb.2019.00329