منابع مشابه
Automatic Identification of Grey Matter Structures from MRI to Improve the Segmentation of White Matter Lesions
The segmentation of MRI scans of patients with white matter lesions (WML) is difficult because the MRI characteristics of white matter lesions are similar to those of grey matter. Intensity based statistical classification techniques misclassify some WML as grey matter and some grey matter as WML. We developed a fast elastic matching algorithm that warps a reference data set containing informat...
متن کاملPathological Differences between White Matter and Grey Matter Multiple Sclerosis Lesions
Multiple Sclerosis (MS) is a debilitating disease and is characterized by demyelination of the central nervous system (CNS) resulting in the wide-spread formation of white matter lesions (WML) and grey matter lesions (GML). WML are pathologically characterized by the presence of immune cells that infiltrated into the CNS, whereas in GML these are hardly present. This striking pathological diffe...
متن کاملGrey matter volume in a large cohort of MS patients: relation to MRI parameters and disability.
BACKGROUND Although grey matter damage in multiple sclerosis is currently recognized, determinants of grey matter volume and its relationship with disability are not yet clear. OBJECTIVES The objectives of the study were to measure grey and white matter volumes across different disease phenotypes; identify MRI parameters associated with grey matter volume; and study grey and white matter volu...
متن کاملDIR-visible grey matter lesions and atrophy in multiple sclerosis: partners in crime?
BACKGROUND The extent and clinical relevance of grey matter (GM) pathology in multiple sclerosis (MS) are increasingly recognised. GM pathology may present as focal lesions, which can be visualised using double inversion recovery (DIR) MRI, or as diffuse pathology, which can manifest as atrophy. It is, however, unclear whether the diffuse atrophy centres on focal lesions. This study aimed to de...
متن کاملHigh field (9.4 Tesla) magnetic resonance imaging of cortical grey matter lesions in multiple sclerosis.
Multiple sclerosis is an inflammatory, degenerative disease of the central nervous system. The most obvious pathological change in multiple sclerosis is multifocal demyelination of the white matter, but grey matter demyelination may be of equal or even greater importance for its clinical manifestations. In order to assess the pathogenetic role of lesions in the grey and white matter, and to exp...
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ژورنال
عنوان ژورنال: Prion
سال: 2013
ISSN: 1933-6896,1933-690X
DOI: 10.4161/pri.22580