Gout with normal serum urate concentration.
نویسندگان
چکیده
منابع مشابه
Acute gout attack with normal serum uric acid levels.
AIM The paper aims to determine the prevalence of clinical cases with acute gout attacks and normal serum uric acid levels. MATERIAL AND METHODS This retrospective study was conducted between October, 2013 and June, 2014 in 30 patients diagnosed with acute gout attack admitted to the 1st Clinic of Rheumatology of Iasi. The diagnosis was based on clinical manifestations and positive response t...
متن کاملSerum urate and incidence of kidney disease among veterans with gout.
OBJECTIVE To study the association between serum urate level (sUA) and the risk of incident kidney disease among US veterans with gouty arthritis. METHODS From 2002 through 2011 adult male patients with gout who were free of kidney disease were identified in the data from the Veterans Administration VISN 16 database and were followed until incidence of kidney disease, death, or the last avail...
متن کاملAdherence with urate-lowering therapies for the treatment of gout
INTRODUCTION Adherence to urate-lowering drugs (ULDs) has not been well evaluated among those with gout. Our aim was to assess the level and determinants of non-adherence with ULDs prescribed for gout. METHODS We identified persons using two integrated delivery systems aged 18 years or older with a diagnosis of gout who initiated use of allopurinol, probenecid or sulfinpyrazone from 1 January...
متن کاملFebuxostat in gout: serum urate response in uric acid overproducers and underexcretors.
OBJECTIVE Hyperuricemia of gout can arise due to either overproduction or underexcretion of uric acid. Not all available urate-lowering therapies are equally effective and safe for use in patients with renal disease. The objective of this post-hoc analysis was to determine the effectiveness of the xanthine oxidase inhibitor febuxostat in reducing serum urate (sUA) levels in gouty patients who w...
متن کاملCoevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout
Uric acid is the highly insoluble end-product of purine metabolism in humans. Serum levels exceeding the solubility threshold can trigger formation of urate crystals resulting in gouty arthritis. Uric acid is primarily excreted through the kidneys with 90% reabsorbed back into the bloodstream through the uric acid transporter URAT1. This reabsorption process is essential for the high serum uric...
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ژورنال
عنوان ژورنال: BMJ
سال: 1977
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.6062.685-a