Good servants, poor masters

Partner Technologies: an alternative to technology masters & servants

There are activities where a dynamic, creative partnership among equals seems like an appropriate model of empowerment. Not only do good partnerships seem to help people attain or sustain powerful engagement in their current activities, in some cases they seem to enable people to successfully enter new activities. In this paper we describe our initial work to develop partner technologies. Using...

Hypothalamic tanycytes—masters and servants of metabolic, neuroendocrine, and neurogenic functions

There is a resurgent interest in tanycytes, a radial glial-like cell population occupying the floor and ventro-lateral walls of the third ventricle (3V). Tanycytes reside in close proximity to hypothalamic neuronal nuclei that regulate appetite and energy expenditure, with a subset sending projections into these nuclei. Moreover, tanycytes are exposed to 3V cerebrospinal fluid and have privileg...

Lords of Poverty and Servants of the Poor

According to British author Graham Hancock, one can get quite rich attending to the poor. His book, Lords of Poverty, * is a scathing indictment of official "overseas development assistance," that collection of efforts of bilateral and multilateral organizations allegedly about the business of transferring resources from the rich, industrialized North to the poor, underdeveloped South. Hancock'...

Steroid receptor coactivators: servants and masters for control of systems metabolism.

Coregulator recruitment to nuclear receptors (NRs) and other transcription factors is essential for proper metabolic gene regulation, with coactivators enhancing and corepressors attenuating gene transcription. The steroid receptor coactivator (SRC) family is composed of three homologous members (SRC-1, SRC-2, and SRC-3), which are uniquely important for mediating steroid hormone and mitogenic ...

Is Growth Good Enough for the Poor?